March Madness Sweet Sixteen Ole Miss vs. Michigan State Betting Picks (03/28/2025)

March Madness Sweet Sixteen Ole Miss vs. Michigan State Betting Picks (03-28-2025)

Michigan State has pleased gamblers as one of the most profitable teams on the March Madness lines board this season. On Friday, the Spartans meet the upstart Ole Miss Rebels, with the winner advancing to the Elite Eight. Namely, Tom Izzo of the Michigan State Spartans is engineering the greatest college basketball coaching turnaround in recent memory. Izzo, 70, has been told to retire in recent years. Instead, Izzo has his team in the Sweet Sixteen for the second time in three seasons after leading the Spartans to the Big Ten regular season title.

2025 NCAA Tournament Sweet Sixteen Friday Ole Miss Rebels vs. Michigan State Spartans

Date and Time:Friday, March 28, 2025, 7:09 p.m. ET
Location:State Farm Arena, Atlanta, GA
TV Coverage:CBS
Odds at SBG Sportsbook
TeamSpreadTotalML
Ole Miss+3½ -106143½ -105+148
Michigan State-3½ -114143½ -115-168
Bet Now on this Game

Ole Miss Rebels Team Overview

Late on, Mississippi has covered the total in four of its previous six games, and Ole Miss has gone over the sportsbook total in six of its last eight outings. First among Mississippi scorers is Sean Pedulla, who averages 15.2 points per game.

Overall, the Mississippi Rebels are 22-11 straight up, 15-15-1 against the spread, and 16-15 over/under the total. Ole Miss has national metrics of 94th for scoring offense, 208th for field goal percentage, 173rd for 3-point field goal percentage, 122nd for free throw percentage, and 316th for offensive rebounding. Defensively, Mississippi is 180th for scoring defense, 145th for field goal percentage permitted, 126th for 3-point field goal percentage allowed, and 314th for defensive rebounding.

Michigan State Spartans Team Overview

Late on, Michigan State has covered nine of its previous ten games and has gone under the NCAA Tournament odds total in eight of its last ten outings. First among Michigan State scorers is Jaden Akins, with 12.7 points per game.

Overall, the Michigan State Spartans are 27-6 straight up, 21-9-1 against the spread, and 10-21 over/under the total. Michigan State has national metrics of 76th for scoring offense, 104th for field goal percentage, 330th for 3-point field goal percentage, 19th for free throw percentage, and 11th for offensive rebounding. Defensively, Michigan State is 49th for scoring defense, 25th for field goal percentage permitted, 2nd for 3-point field goal percentage allowed, and 29th for defensive rebounding.

Jaden Akins scored a team-high 16 points Sunday night. Hence, second-seeded Michigan State controlled the last seven minutes to eliminate 10th-seeded New Mexico 71-63.

Tre Holloman came off the bench to add 14 points, and fellow reserve Frankie Fidler chipped in 10 points for the Spartans. As a result, MSDU will advance to the regional semifinals in Atlanta to play No. 6 Ole Miss on Friday. The Rebels were 91-78 winners over third-seeded Iowa State.

Nelly Junior Joseph scored 16 points for the Lobos. But he was limited to 29 minutes due to foul trouble before fouling out at the 2:12 mark. Mountain West Conference Player of the Year Donovan Dent added 14 points and six assists. Also, Mustapha Amzil tallied 14 points.

New Mexico canned 48.2 percent of its field goal attempts. Including 15 of 28 in the second half. It outshot Michigan State, which made 44.4 percent from the field, but the Spartans won this one at the foul line. They converted 19 of 28 there, while the Lobos made just 5 of 10.

Ole Miss vs. Michigan State SBG Free Picks

As mentioned earlier, Michigan State is a strong betting value this season.

Ole Miss vs. Michigan State SBG Best Bet: Michigan State Spartans.