March Madness odds have the Clemson Tigers favored on Thursday in the NCAA Tournament against the Michigan Wolverines. The Tigers are the 7th seed in the South Regional while the Wolverines are the 10th seed. March Madness betting statistics tell us that Michigan is 20-13 on the season straight up and 15-11-1 against the spread while Clemson is 23-8 straight up and 12-13-1 against the number.