Week: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | Bowl
WEEK 4 | |
Thursday, September 24 | |
| TIME | MATCHUP |
| 7:30 p.m. | No. 8 Mississippi at South Carolina |
Friday, September 25 | |
| TIME | MATCHUP |
| 9:00 p.m. | Missouri at Nevada |
Saturday, September 26 | |
| TIME | MATCHUP |
| TBA | No. 1 Florida at Kentucky |
| TBA | Washington State at No. 4 USC |
| TBA | Arkansas at No. 5 Alabama |
| TBA | Illinois at No. 6 Ohio State |
| TBA | Miami (FL) at No. 7 Virginia Tech |
| TBA | No. 11 LSU at Mississippi State |
| TBA | Arizona State at No. 13 Georgia |
| TBA | No. 21 North Carolina at No. 15 Georgia Tech |
| TBA | No. 17 TCU at Clemson |
| TBA | South Florida at No. 18 Florida State |
| TBA | Ball State at Auburn |
| TBA | Army at Iowa State |
| TBA | Minnesota at Northwestern |
| TBA | Wake Forest at Boston College |
| TBA | Rutgers at Maryland |
| TBA | Maine at Syracuse |
| TBA | Arizona at Oregon State |
| TBA | Michigan State at Wisconsin |
| TBA | Troy at Arkansas State |
| TBA | Ohio at Tennessee |
| 12:00 p.m. | Southern Miss at No. 25 Kansas |
| 12:00 p.m. | Rhode Island at Connecticut |
| 12:00 p.m. | Indiana at Michigan |
| 12:00 p.m. | Buffalo at Temple |
| 12:00 p.m. | Fresno State at Cincinnati |
| 2:00 p.m. | San Diego State at Air Force |
| 2:10 p.m. | Tennessee Tech at Kansas State |
| 3:00 p.m. | UNLV at Wyoming |
| 3:30 p.m. | UTEP at No. 2 Texas |
| 3:30 p.m. | No. 12 California at No. 16 Oregon |
| 3:30 p.m. | UCF at East Carolina |
| 3:30 p.m. | Pittsburgh at North Carolina State |
| 3:30 p.m. | Akron at Central Michigan |
| 3:30 p.m. | Western Kentucky at Navy |
| 3:30 p.m. | Idaho at Northern Illinois |
| 3:30 p.m. | McNeese State at Tulane |
| 4:00 p.m. | Louisiana-Monroe at Florida Atlantic |
| 6:00 p.m. | Colorado State at No. 20 Brigham Young |
| 7:00 p.m. | Grambling State at No. 9 Oklahoma State |
| 7:00 p.m. | No. 14 Boise State at Bowling Green |
| 7:00 p.m. | Louisiana-Lafayette at No. 24 Nebraska |
| 7:00 p.m. | North Carolina Central at Duke |
| 7:00 p.m. | Sam Houston State at Tulsa |
| 7:00 p.m. | Northwestern State at Baylor |
| 7:00 p.m. | UAB at Texas A&M |
| 7:00 p.m. | Middle Tennessee State at North Texas |
| 7:00 p.m. | Toledo at Florida International |
| 7:00 p.m. | Miami (OH) at Kent State |
| 7:00 p.m. | Hofstra at Western Michigan |
| 7:30 p.m. | Louisville at No. 19 Utah |
| 8:00 p.m. | No. 22 Iowa at No. 9 Penn State |
| 8:00 p.m. | No. 23 Notre Dame at Purdue |
| 8:00 p.m. | Cal Poly at San Jose State |
| 8:00 p.m. | Marshall at Memphis |
| 8:00 p.m. | Vanderbilt at Rice |
| 8:00 p.m. | Southern Utah at Utah State |
| 9:00 p.m. | Washington at Stanford |
| 9:15 p.m. | Texas Tech at Houston |
| 10:00 p.m. | New Mexico State at New Mexico |