NFL betting fans can already begin wagering on the Week 1 odds in anticipation of the upcoming football betting season. NFL enthusiasts who place bets on the Week 1 football betting lines well before the season begins have the advantage of placing wagers before these NFL betting lines shift, as many likely will do. Nevertheless, such NFL must be undertaken with a realization that significant injuries can occur before the Week 1 games actually take place, so NFL betting fans should follow the injury news carefully.