San Francisco 49ers vs. Arizona Cardinals NFL Week 11 Picks & Odds (11/21/2022)

San Francisco 49ers vs. Arizona Cardinals NFL Week 11 Picks & Odds (11-21-2022)

Last week the Cardinals scored a stunning win at the Rams. It was a game featuring backup quarterbacks for each side. But the Cardinals will not apologize for the Pro Football betting payoff. Arizona and coach Kliff Kingsbury desperately needed a win and got it. Now the Cardinals are keeping their playoff hopes alive. But there is no rest for the weary in the NFL. Especially in the highly competitive NFC West. Arizona will host the 49ers on Monday Night. And San Francisco is coming off an impressive Sunday night win over the Chargers.

San Francisco 49ers vs. Arizona Cardinals NFL Betting Information

Date and Time:Monday, November 21, 2022, 8:15 p.m. ET
Location:Estadio Azteca, Mexico City
TV Coverage:ESPN SoFi Stadium, Inglewood, California
Odds at SBG Sportsbook
TeamSpreadTotalML
49ers-8 (-110)43½ (-110)-370
Cardinals+8 (-110)43½ (-110)+295
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49ers vs. Cardinals SBG Odds Overview

San Francisco is the bigger sports betting brand and will draw most of the square support at the betting window. The Cardinals will draw support from casual gamblers that always prefer the home side. Thus, oddsmakers don’t expect an imbalance of betting action.

San Francisco 49ers Team Overview

Last game, the San Francisco 49ers won 22-16 against the Los Angeles Chargers as 8.5-point home favorites. The game went under the total of 45.5. San Francisco has a record of 5-4 straight up, 4-5 against the spread, and 3-6 over/under the total.

San Francisco had its usual winning formula of running run the ball effectively for key stages of the game. In turn, they control the time of possession and try to avoid any bad decisions from quarterback Jimmy Garoppolo. Accordingly, the 49ers passer didn’t record a single turnover-worthy play in the contest. And he even added a big-time throw on one of his five pressured dropbacks.

In turn, the entire 49ers’ defense showed out positively against the Chargers. This group has established itself as a fast and physical unit. Against the Chargers, they flew to the ball all night. The defense missed just one tackle. Also, they allowed 0.1 yards before contact per attempt on runs. Additionally, the Niners recorded nine defensive stops on the 22 passes Justin Herbert threw less than 10 yards downfield.

To summarize, the Chargers were shut out in the second half. Furthermore, LA was limited to a mere 2.7 yards per play. Herbert spent over a third of his dropbacks under pressure. And when he was presented with a clean pocket, there weren’t many opportunities for him to attack.

Arizona Cardinals Team Overview

Last game, the Arizona Cardinals won 27-17 against the Los Angeles Rams as 3.5-point road dogs. The game went over the total of 37.5. Arizona has a record of 4-6 straight up, 5-5 against the spread, and 5-5 over/under the total.

Namely, Colt McCoy performed admirably in relief of Kyler Murray, who was nursing a hamstring injury. The 13th-year quarterback earned an 83.5 grade on the first review. The former Texas great also tossed two big-time throws. And McCoy had no turnover-worthy plays in the win.

Cardinal cornerback Antonio Hamilton had a career game against the Rams. To show, Hamilton forced two incompletions and allowed only 22 yards on nine targets. Also, he impressed as a run defender, producing two stops.

49ers vs. Cardinals SBG Free Picks

In this situation, the 49ers are the more complete Pro Football Betting value.

49ers vs. Cardinals SBG Best Bet: San Francisco 49ers.