San Francisco 49ers vs. Denver Broncos NFL Week 3 Odds & Picks (09/25/2022)

Last summer, the Broncos were one of the hottest brands going. New head coach Nathanial Hackett brought offensive success and hope from Green Bay. Most important of all, Russell Wilson arrived as the missing QB piece from Seattle. Wilson is the quarterback that Denver has needed for the past several betting on NFL seasons. However, the Broncos and Wilson are struggling to get in sync after two games. Meanwhile, 49er QB Jimmy Garoppolo has seen his career be reborn. But under unfortunate circumstances. Jimmy G is back under center after the season-ending injury to Trey Lance.

San Francisco 49ers vs. Denver Broncos NFL Betting Information

Date and Time:Sunday, September 25, 2022,8:20 p.m. ET
Location:Empower Field at Mile High, Denver, Colorado
TV Coverage:NBC
Odds at SBG Sportsbook
TeamSpreadTotalML
49ers-1½ (-110)45 (-110)-125
Broncos+1½ (-110)45 (-110)+105
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49ers at Broncos SBG Odds Overview

Certainly, there will be an avalanche of online betting action for this Sunday night marquee matchup. San Francisco enters this game with the QB that took them to the 2021 NFC championship game. And Russell Wilson is going against his old hated rivals from his days at Seattle. To summarize, the betting handle will be split for both sides.

San Francisco 49ers Team Overview

Last time out, San Francisco scored a 27-7 win against Seattle as 8.5-point home favorites. Also, the game went under the total of 40.5. San Francisco has a record of 1-1 straight up, 1-1 against the spread, and 0-2 over/under the total.

Following the season-ending injury to Trey Lance, the 49ers returned to an old hand as QB. Jimmy Garoppolo was nearly traded in the offseason. Now the 49ers are thanking their lucky stars he was not. Indeed, it was a reminder that some of the best blessings are prayers that go unanswered. Jimmy G posted a 100.1 QB rating in his return off the bench. He threw for 154 yards and a TD. Additionally, Garoppolo had a TD run.

Also contributing to the 49ers was Jeffrey Wilson with 84 yards on 18 rushes with four first downs. Nick Bosa added two sacks. And the 49ers outgained the Seahawks 373 to 216 in total yards. Seattle could muster only 36 yards on the ground.

Certainly, nobody likes to see what happened to Lance. But there is a case that can be made for Garoppolo being more of a proven asset.

Denver Broncos Team Overview

Last time out, Denver scored a 16-9 win against Houston as 10.5-point home favorites. The game went under the total of 45. Denver has a record of 1-1 straight up, 0-2 against the spread, and 0-2 over/under the total.

At the onset of the 4th quarter, Denver trailed the lowly Texans 9-6. Finally, in that frame, Wilson found the mark. He hit Eric Saubert on a 22-yard go-ahead TD pass.

In sum, Denver outgained Houston 350 to 234 in total yards. However, the Broncos committed a whopping 13 penalties. Wilson finished with a lackluster 66.5 QB rating. He was 14 of 31 for 219 yards with one TD and one INT.

49ers at Broncos SBG Free Picks

Last week’s comeback win is a spark for the Broncos. In turn, the Broncos realize they must step up their Betting on NFL game this week. Also, the Broncos want to atone for their Monday Night TV flop in week one at Seattle.

49ers at Broncos SBG Best Bet: Denver Broncos.