NFL Week 16 odds offer some hugely exciting match ups within the NFC East. Week 16 odds feature numerous exciting match ups, with one of the principal ones being the Packers-Bears game. The NFL sports odds spreads Week 16 have the Bears has slight favorites in this match up, partly because it will be played at Soldier Field, but those betting on the Week 16 odds should take into account that Favre and the Packers will be looking for revenge after their loss to Chicago earlier in the season.