Week: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | Bowl
Week 12 | |
Wednesday, November 18 | |
| TIME | MATCHUP |
| TBA | Buffalo at Miami (OH) |
| TBA | Central Michigan at Ball State |
Thursday, November 19 | |
| TIME | MATCHUP |
| 7:30 p.m. | Colorado at No. 5 Oklahoma State |
Friday, November 20 | |
| TIME | MATCHUP |
| 5:30 p.m. | Akron at Bowling Green |
| 7:00 p.m. | Eastern Michigan at Toledo |
| 9:30 p.m. | No. 12 Boise State at Utah State |
Saturday, November 21 | |
| TIME | MATCHUP |
| TBA | Florida International at No. 1 Florida |
| TBA | No. 24 Kansas at No. 2 Texas |
| TBA | Chattanooga at No. 4 Alabama |
| TBA | No. 11 LSU at No. 6 Mississippi |
| TBA | No. 7 Penn State at Michigan State |
| TBA | No. 8 Ohio State at Michigan |
| TBA | No. 10 California at Stanford |
| TBA | No. 13 Oklahoma at Texas Tech |
| TBA | North Carolina State at No. 14 Virginia Tech |
| TBA | No. 19 North Carolina at Boston College |
| TBA | Duke at No. 20 Miami (FL) |
| TBA | Kentucky at No. 21 Georgia |
| TBA | Kansas State at No. 22 Nebraska |
| TBA | Iowa State at No. 25 Missouri |
| TBA | Mississippi State at Arkansas |
| TBA | Oregon at Arizona |
| TBA | Arizona State at UCLA |
| TBA | Maryland at Florida State |
| TBA | Louisville at South Florida |
| TBA | Wisconsin at Northwestern |
| TBA | Purdue at Indiana |
| TBA | Rutgers at Syracuse |
| TBA | Virginia at Clemson |
| TBA | Memphis at Houston |
| TBA | Oregon State at Washington State |
| TBA | Minnesota at Iowa |
| TBA | Arkansas State at Middle Tennessee State |
| TBA | Vanderbilt at Tennessee |
| TBA | Florida Atlantic at Troy |
| 1:00 p.m. | Kent State at Temple |
| 2:00 p.m. | No. 16 TCU at Wyoming |
| 2:00 p.m. | Northern Illinois at Ohio |
| 2:00 p.m. | Tulane at UCF |
| 2:30 p.m. | Connecticut at No. 18 Notre Dame |
| 3:30 p.m. | Air Force at No. 9 Brigham Young |
| 3:30 p.m. | UAB at East Carolina |
| 3:30 p.m. | UTEP at Rice |
| 3:30 p.m. | Baylor at Texas A&M |
| 4:00 p.m. | San Diego State at No. 17 Utah |
| 4:00 p.m. | Army at North Texas |
| 4:30 p.m. | Southern Methodist at Marshall |
| 5:00 p.m. | Louisiana Tech at Fresno State |
| 6:00 p.m. | Colorado State at New Mexico |
| 7:00 p.m. | Louisiana-Monroe at Louisiana-Lafayette |
| 7:00 p.m. | Tulsa at Southern Miss |
| 8:00 p.m. | Hawaii at San Jose State |
| 8:00 p.m. | Nevada at New Mexico State |